全文获取类型
收费全文 | 4132篇 |
免费 | 191篇 |
国内免费 | 71篇 |
专业分类
耳鼻咽喉 | 41篇 |
儿科学 | 37篇 |
妇产科学 | 94篇 |
基础医学 | 484篇 |
口腔科学 | 385篇 |
临床医学 | 791篇 |
内科学 | 262篇 |
皮肤病学 | 9篇 |
神经病学 | 134篇 |
特种医学 | 372篇 |
外科学 | 656篇 |
综合类 | 492篇 |
预防医学 | 107篇 |
眼科学 | 23篇 |
药学 | 171篇 |
3篇 | |
中国医学 | 36篇 |
肿瘤学 | 297篇 |
出版年
2024年 | 5篇 |
2023年 | 85篇 |
2022年 | 149篇 |
2021年 | 205篇 |
2020年 | 187篇 |
2019年 | 143篇 |
2018年 | 182篇 |
2017年 | 134篇 |
2016年 | 139篇 |
2015年 | 120篇 |
2014年 | 315篇 |
2013年 | 228篇 |
2012年 | 272篇 |
2011年 | 289篇 |
2010年 | 264篇 |
2009年 | 201篇 |
2008年 | 210篇 |
2007年 | 202篇 |
2006年 | 193篇 |
2005年 | 150篇 |
2004年 | 129篇 |
2003年 | 76篇 |
2002年 | 49篇 |
2001年 | 59篇 |
2000年 | 48篇 |
1999年 | 39篇 |
1998年 | 37篇 |
1997年 | 31篇 |
1996年 | 33篇 |
1995年 | 35篇 |
1994年 | 46篇 |
1993年 | 38篇 |
1992年 | 17篇 |
1991年 | 19篇 |
1990年 | 9篇 |
1989年 | 8篇 |
1988年 | 7篇 |
1987年 | 5篇 |
1986年 | 5篇 |
1984年 | 5篇 |
1983年 | 3篇 |
1982年 | 5篇 |
1981年 | 4篇 |
1980年 | 3篇 |
1979年 | 1篇 |
1978年 | 3篇 |
1977年 | 2篇 |
1976年 | 2篇 |
1975年 | 1篇 |
1973年 | 1篇 |
排序方式: 共有4394条查询结果,搜索用时 15 毫秒
31.
32.
33.
34.
目的 通过三维(3D)打印技术协助新西兰兔个体化钛合金修复体进行预制行颅骨缺损修补,探讨3D技术在颅骨缺损重建中的运用价值。方法 选取健康雄性新西兰兔12只制作颅骨缺损模型成功后,螺旋64排CT薄层无间距逐层扫描获得断层数据后进行格式转换构建三维颅骨立体模型,利用3D打印机进行修复体的三维原型制造,结合模型利用钛合金修复体进行骨性缺损区域精准修补。结果 钛合金修复体与骨性缺损区域及边缘组织契合满意,术中一次固定到位,避免反复剪裁,操作阻力小,伤口均一期愈合,不良反应较少,未观察到颅内感染、头皮溃烂、钛合金外露、排出及移位等不良现象。术后颅骨外形与健侧相比更美观、功能修复满意,并邀请三位同行医师评估修复满意度,以100%为满意,取平均值,满意率为98.78%。结论 与颅骨缺损修补术相比,3D打印技术可快速、精准结合钛合金,对个体化修复颅骨缺损区尤其是复杂解剖形态“适形”可能更胜一筹,值得临床推广运用。 相似文献
35.
G. Hoarau S. Picot J. Lemant J. Peytral P. Poubeau P. Zunic C. Mohr X. Coueffe P. Gerardin E. Antok 《Médecine et maladies infectieuses》2018,48(6):414-418
Objectives
We aimed to describe the epidemiology of Candida bloodstream infection in an intensive care unit (ICU) in Reunion Island.Methods
We performed a retrospective cohort study and evaluated 63 candidemia episodes, which occurred between January 2004 and December 2015 in the ICU of a University Hospital in St-Pierre.Results
The incidence rate of candidemia in the ICU was estimated at 7.6%. Candida albicans was the most common yeast pathogen species recovered (54%), followed by Candida glabrata (17%), Candida tropicalis (12%) and Candida parapsilosis (10%). Between 2012 and 2015, we also observed a modification of antifungal use.Conclusion
The epidemiology of candidemia in Reunion Island is characterized by the predominance of Candida albicans and by the relative importance of Candida tropicalis. This pattern corresponds to a model of epidemiological transition between the one usually observed in tropical areas and the one observed in temperate countries. 相似文献36.
M. Tauzin N. Ouldali C. Lévy S. Béchet R. Cohen L. Caeymaex 《Clinical microbiology and infection》2019,21(8):1006-1012
ObjectivesEscherichia coli is the second cause of bacterial meningitis in neonates. Despite the use for 35 years of third-generation cephalosporins (3GCs), high morbidity and mortality rates with E. coli meningitis continue to occur. Because ciprofloxacin has good microbiologic activity against E. coli and good penetration in cerebrospinal fluid and brain, some authors have suggested adding ciprofloxacin to a 3GC regimen. The objective of this study was to assess combining 3GCs with ciprofloxacin versus 3GCs alone in a cohort of infants with E. coli meningitis.MethodsWe included all cases of E. coli meningitis diagnosed in infants <12 months of age that were prospectively collected through the French paediatric meningitis surveillance network between 2001 and 2016. The main outcome was the proportion of short-term neurologic complications with versus without ciprofloxacin. The analysis was conducted retrospectively by multivariable regression and propensity score (PS) analysis.ResultsAmong the 367 infants enrolled, 201 (54.8%) of 367 had ciprofloxacin and 3GC cotreatment and 166 (45.2%) of 367 only a 3GC. Median age and weight were 15 days (range, 1–318 days) and 3.42 kg (range, 0.66–9.4 kg). A total of 86 (23.4%) of 367 infants presented neurologic complications (seizures, strokes, empyema, abscesses, hydrocephalus, arachnoiditis); 57 received ciprofloxacin cotreatment. Complications were associated with ciprofloxacin cotreatment on multivariable analysis (odds ratio (OR) = 1.9; 95% confidence interval (CI), 1.1–3.4) and PS analysis (OR = 1.9; 95% CI, 1.1–3.3). Mortality rate did not differ with and without ciprofloxacin: 22 (10.9%) of 201 versus 16 (9.6%) of 166 deaths (OR = 0.7; 95% CI, 0.3–1.6; PS analysis).ConclusionsCiprofloxacin added to 3GCs at least offers no advantage for neurologic outcome and mortality in infants with E. coli meningitis. 相似文献
37.
KyungWook Nha Young Jun Nam Myung Jin Shin Seung Deok Sun Jae Young Park Rajib Debnath Byung Hoon Lee 《The Knee》2019,26(6):1429-1436
BackgroundTo determine whether 3D-CT imaging technique is valid and reproducible compared to conventional CT measurement technique (CCT) for the detection of a femoropatellar instability.MethodsPatients who had undergone surgery for femoropatellar instability (patellar instability group) between 2010 and 2016 (n = 37 knees of 35 patients) were retrospectively enrolled. For the matched control group, patients who had acute anterior cruciate ligament injury (< 4 weeks previously; n = 30) were recruited. Preoperative CT data had been obtained in all patients. Inter-rater reliability was calculated for both measurement protocols, and inter-method reliability was calculated between the two imaging modalities. The results are reported using intraclass correlation coefficients (ICCs) and Bland–Altman 95% limits of agreement.ResultsAll patients in the patellar instability group had femoral trochlear dysplasia (Dejour types A: four, B: 19, C: seven, and D: six), but no dysplasia was noted in the control group. In the patellar instability group, the CCT technique showed a poor inter-rater agreement (ICC = 0.74), and the 3D-CT technique still showed excellent inter-rater agreement (ICCs = 0.91). In the sub-analysis of the patellar instability group according to the trochlear dysplasia grade, ICCs were markedly decreased with severe trochlear dysplasia when using CCT technique; however, the 3D-CT technique could provide excellent reliability even with severe trochlear dysplasia.ConclusionThe 3D-CT imaging technique for the measurement of the TT–TG distance can be suggested as a better measurement technique for patellar instability patients with bone abnormality. 相似文献
38.
Cultural animation in health research: An innovative methodology for patient and public involvement and engagement 下载免费PDF全文
Mihaela Kelemen BA PhD DPhil Emma Surman BSc PhD Lisa Dikomitis BA MA PhD 《Health expectations》2018,21(4):805-813
Background
A significant challenge in Patient and Public Involvement and Engagement (PPIE) in health research is to include a wide range of opinions and experiences, including from those who repeatedly find themselves at the margins of society.Objective
To contribute to the debate around PPIE by introducing a bottom‐up methodology: cultural animation (CA). Cultural Animation is an arts‐based methodology of knowledge co‐production and community engagement which employs a variety of creative and participatory exercises to help build trusting relationships between diverse participants (expert and non‐experts) and democratize the process of research.Design
Three CA full‐day workshops for the research project “A Picture of Health.”Participants
Each workshop was attended by 20‐25 participants including 4 academics, 5 retired health professionals who volunteered in the local community and 15 community members. Participants ranged in age from 25 to 75 years, and 80% of the participants were women over the age of 60.Results
The CA workshops unearthed a diversity of hidden assets, increased human connectivity, led to rethinking of and co‐creating new health indicators and enabled participants to think of community health in a positive way and to consider what can be developed.Discussion
Cultural animation encourages participants to imagine and create ideal pictures of health by experimenting with new ways of working together.Conclusion
We conclude by highlighting the main advantages to PPIE as follows: CA provides a route to co‐produce research agendas, empowers the public to engage actively with health professionals and make a positive contribution to their community. 相似文献39.
全口义齿咬合接触的三维测量分析 总被引:1,自引:0,他引:1
目的采用三维数字化方法对咬合接触参数进行测量分析。方法应用非接触式激光三维扫描和三维数字化技术,在三维扫描和重建10副全口义齿人工牙面以及正中时咬合状态的基础上,测定咬合接触的数目和部位,并与T-Scan咬合仪的测量结果进行配对t检验。结果⑴咬合接触参数的测量结果显示,咬合接触区域主要集中在磨牙和前磨牙区;⑵应用激光扫描系统测量和T-Scan系统测量的咬合接触部位和数目比较,P>0.05,在统计学上无显著性差异。结论本研究将激光扫描技术引入全口义齿咬合接触研究领域,通过测量全口义齿咬合接触部位和数目,并与T-Scan系统的测量结果进行比较,进一步验证了该方法进行咬合检测的可靠性,为今后咬合接触的研究提供了新的思路。 相似文献
40.